The college has set out three key areas of concern with changes proposed under the review, which would see health visitors relocated into multi-professional teams led by social services management.
RCGP Scotland says that immunisation rates could fall, post-natal depression could go undetected and child protection could suffer.
Its chair Dr Ken Lawton said that the reorganisation would threaten existing relationships between health visitors and patients, which are responsible for currently high immunisation rates.
He added that these relationships were key to maintaining high rates of breastfeeding, early detection of children at risk of abuse and identifying post-natal depression.
Dr Lawton said: 'RCGP Scotland is deeply concerned about the potential damage to the vital relationship health visitors have with patients.'
Around 21,000 signatures have been collected in petitions against the proposals and will be delivered to parliament on 29 October.
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